THE LONG NONCODING RNA MIR4435-2HG ENHANCES THE MIGRATION, PROMOTION, AND GLYCOLYSIS OF NONSMALL CELL LUNG CANCER CELLS BY TARGETING THE MIR-371A-5P/SOX2/PI3K/AKT AXIS

Background: Nonsmall cell lung cancer is a leading cause of cancer-related death worldwide.The long noncoding RNA MIR4435-2HG has been shown to play a carcinogenic role in various cancers.The purpose of this study was to explore the role and regulatory mechanism of MIR4435-2HG in non-small cell lung cancer.Methods: Quantitative real-time polymerase

Abstract Chronic psychosocial stress induced by the vibrating-sex-toys-and-dildos chronic subordinate colony housing (CSC, 19 Days) paradigm promotes functional splenic in vitro glucocorticoid (GC) resistance, but only if associated with significant bite wounding or prior abdominal transmitter implantation.Moreover, sensory contact to social defeat

ABSTRACT Uncultured and therefore uncharacterized Bacteroidetes lineages are ubiquitous in many natural ecosystems which specialize in lignocellulose degradation.However, their metabolic contribution remains mysterious, as well-studied cultured Bacteroidetes have been shown to vibrating-sex-toys-and-dildos degrade only soluble polysaccharides withi